Web13 okt. 2024 · Elesclomol shows antitumor activity against a broad range of cancer cell types. Moreover, Elesclomol is also a highly lipophilic Cu2+-binding molecule. In vitro, Elesclomol (200 nM; 18 hours) treatment increases the number of early and late apoptotic HSB2 cells. Web1 jul. 2008 · The HSB2 cell line was originally derived from a T-ALL patient, whereas PBL comprise mainly T cells (72%), B cells (13%), and natural killer cells (14%). Both C-type lectins bind >90% of the HSB2 cells, whereas a much lower specific binding to PBL was observed (Fig. 1 A).
Elesclomol (STA-4783) is an Oxidative Stress Inducer and Induces ...
Web11 jul. 2012 · Jurkat and HSB2 cells were preactivated with collagen (Col) or left unstimulated (NT) for 4 h and were then treated with doxorubicin (Dox) for 2 h. mRNA levels for the different ABC transporters and for β-actin were determined by reverse transcriptase-PCR using specific primers ( Table 1 ). Web11 jan. 2024 · Nelarabine is a chemotherapy drug used in T-cell acute lymphoblastic leukemia. IC50 Value: 0.44 uM (HSB2 cell lines); 1.24 μM (ALL-SIL cell lines); 2.15 μM (JURKAT cell lines); 0.067 uM (PER-255 cell lines) [1]Target: Nucleoside antimetabolite/analogin vitro: The IC50 of Nelarabine is 25-fold and 113-fold higher than … how to start with clickbank aff
Impact of HHV-6A and HHV-6B lytic infection on autophagy and ...
Web1 dec. 1998 · The involvement of bcl-2 activity, established a close association between small vitamin molecules particularly DCaP, CC or Rb and the biochemical activation of apoptosis, which prevented cell proliferation from reaching maximum capacity while increasing cell death rate. 60 WebDownload scientific diagram MAP Kinase and Stat pathway activation in response to MerTK Gas6 stimulation. (a) Analysis of phosphorylation status of MerTK in Jurkat and … Web7 sep. 2011 · Leukemia cell lines were obtained from the American Type Culture Collection (ATCC; Molt-4) or were generously provided by Dr. Terzah Horton, Baylor College of Medicine (Reh, RS4, Jurkat, JM1, and HSB2). Cell line authentication was done after all studies had been completed by PCR amplification of 9 short tandem repeat (STR) loci … react native text next line