WebMar 28, 2024 · To further investigate the biological consequences of TTC21A mutations in MMAF-affected men and the roles of TTC21A in sperm flagellar formation, we employed CRISPR-Cas9 technology to generate C57BL/6 mutant mice harboring a Ttc21a frameshift mutation. 30, 31 The single-guide RNA (sgRNA) that was used in this study was … WebMar 21, 2024 · TTC21A (Tetratricopeptide Repeat Domain 21A) is a Protein Coding gene. Diseases associated with TTC21A include Spermatogenic Failure 37 and Non-Syndromic …
Increased expression of TTC21A in lung adenocarcinoma …
WebApr 10, 2024 · Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice. The genetic architecture of morphological abnormalities of the sperm tail. Homozygous mutations in DZIP1 can induce asthenoteratospermia with severe MMAF. Biallelic variants in MAATS1 encoding CFAP91, … WebTTC21A INFORMATION. Proteini. Full gene name according to HGNC. Tetratricopeptide repeat domain 21A. Gene namei. Official gene symbol, which is typically a short form of … flandreau crystal theatre
High expression of TTC21A predict poor prognosis of colorectal …
WebA disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a … WebExpression of TTC21A (IFT139A, STI2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. WebIncreased TTC21A expression in lung adenocarcinoma tissues is significantly correlated with pathological stage, tumor status and lymph nodes. Up-regulated TTC21A expression, … flandreau county